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CP16: Preparation of Aspirin

Preparation, purification and testing of aspirin (2-acetoxybenzoic acid)

Required PracticalEdexcelA-Level

๐Ÿ”ฌ Equipment Required

  • 2-hydroxybenzoic acid (salicylic acid)
  • Ethanoic anhydride
  • Concentrated phosphoric acid (catalyst)
  • Water bath
  • Ice bath
  • Buchner funnel and flask
  • Filter paper
  • Melting point apparatus
  • Recrystallisation equipment
  • Iron(III) chloride solution (for purity test)

๐Ÿฆบ Safety Precautions

  • Wear safety glasses
  • Ethanoic anhydride is corrosive and lachrymatory
  • Work in fume cupboard
  • Phosphoric acid is corrosive
  • Product is for analysis only - DO NOT INGEST
  • Allow apparatus to cool before handling

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About CP16: Preparation of Aspirin

CP16: Preparation of Aspirin is a required practical for Edexcel A-Level Chemistry. This practical preparation, purification and testing of aspirin (2-acetoxybenzoic acid)

Students are expected to understand the method, identify and control variables, use appropriate equipment, analyse results, draw graphs, identify sources of error, suggest improvements, and consider safety precautions.

Questions on required practicals frequently appear in Edexcel A-Level Chemistry exams and can be worth significant marks. Practice with our AI-generated questions to master this practical.

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